GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2243480 | 1 | rs6949812 | chr7:65387101 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 4.97 | 3.0E-6 | Diabetic kidney disease |
| THYM | cis | rs1451375 | 1 | rs6949897 | chr7:50621920 | FIGNL1 | chr7:50511834-50518088:- | -0.3 | -4.64 | 1.09E-5 | Malaria |
| THYM | cis | rs568617 | 1 | rs694994 | chr11:65653309 | CTSW | chr11:65647284-65651212:+ | -0.59 | -7.12 | 2.04E-10 | Crohn's disease |
| THYM | cis | rs568617 | 1 | rs694994 | chr11:65653309 | SNX32 | chr11:65601410-65621170:+ | 0.55 | 5.17 | 1.29E-6 | Crohn's disease |
| THYM | cis | rs2243480 | 1 | rs6958289 | chr7:65657111 | CCT6P1 | chr7:65216092-65228661:+ | -0.67 | -5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs6958420 | chr7:65751171 | CCT6P1 | chr7:65216092-65228661:+ | -0.64 | -5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs6959002 | chr7:65650496 | CCT6P1 | chr7:65216092-65228661:+ | -0.67 | -5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs6964245 | chr7:65718717 | CCT6P1 | chr7:65216092-65228661:+ | -0.64 | -5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs6964530 | chr7:65718851 | CCT6P1 | chr7:65216092-65228661:+ | -0.64 | -5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs6966322 | chr7:65646754 | CCT6P1 | chr7:65216092-65228661:+ | -0.67 | -5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs6970243 | chr7:65388490 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 4.97 | 3.0E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs6974723 | chr7:65637939 | CCT6P1 | chr7:65216092-65228661:+ | -0.67 | -5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs7017914 | 1 | rs7007450 | chr8:71640269 | XKR9 | chr8:71581600-71648176:+ | 0.84 | 10.55 | 1.11E-17 | Bone mineral density |
| THYM | cis | rs7017914 | 1 | rs7017914 | chr8:71591203 | XKR9 | chr8:71581600-71648176:+ | 0.84 | 10.55 | 1.11E-17 | Bone mineral density |
| THYM | cis | rs1875620 | 1 | rs7019938 | chr9:91564344 | C9orf47 | chr9:91605778-91611055:+ | -0.27 | -4.71 | 8.28E-6 | Response to statins (LDL cholesterol change) |